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PDGFR-β restores blood-brain barrier functions in a mouse model of focal cerebral ischemia

Although platelet-derived growth factor receptor beta (PDGFR-β) mediates the recruitment of vascular pericytes into ischemic lesion to restore the blood-brain barrier (BBB) dysfunction, its mechanisms still remain elusive. Compared with control PDGFR-β(floxed)(/)(floxed) mice (Floxed), postnatally i...

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Detalhes bibliográficos
Publicado no:J Cereb Blood Flow Metab
Main Authors: Shen, Jie, Xu, Guihua, Zhu, Runxiu, Yuan, Jun, Ishii, Yoko, Hamashima, Takeru, Matsushima, Takako, Yamamoto, Seiji, Takatsuru, Yusuke, Nabekura, Junichi, Sasahara, Masakiyo
Formato: Artigo
Idioma:Inglês
Publicado em: SAGE Publications 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6681529/
https://ncbi.nlm.nih.gov/pubmed/29629621
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/0271678X18769515
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