The Novel Pathogenesis of Retinopathy Mediated by Multiple RTK Signals is Uncovered in Newly Developed Mouse Model

Pericyte desorption from retinal blood vessels and subsequent vascular abnormalities are the pathogenesis of diabetic retinopathy (DR). Although the involvement of abnormal signals including platelet-derived growth factor receptor-β (PDGFRβ) and vascular endothelial growth factor-A (VEGF-A) have bee...

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Salvato in:
Dettagli Bibliografici
Pubblicato in:EBioMedicine
Autori principali: Kitahara, Hideyuki, Kajikawa, Sayaka, Ishii, Yoko, Yamamoto, Seiji, Hamashima, Takeru, Azuma, Erika, Sato, Hikari, Matsushima, Takako, Shibuya, Masabumi, Shimada, Yutaka, Sasahara, Masakiyo
Natura: Artigo
Lingua:Inglês
Pubblicazione: Elsevier 2018
Soggetti:
Research Paper
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6013936/
https://ncbi.nlm.nih.gov/pubmed/29724654
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2018.04.021
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