Serine racemase deletion attenuates neurodegeneration and microvascular damage in diabetic retinopathy

Diabetic retinopathy (DR) is a leading cause of blindness. DR is recognized as a microvascular disease and inner retinal neurodegeneration. In the course of retinal neurodegeneration, N-methyl-D-aspartate receptor (NMDAR)-mediated excitotoxicity is involved. Full activation of NMDAR requires binding...

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Enregistré dans:
Détails bibliographiques
Publié dans:PLoS One
Auteurs principaux: Ozaki, Hironori, Inoue, Ran, Matsushima, Takako, Sasahara, Masakiyo, Hayashi, Atsushi, Mori, Hisashi
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2018
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5755926/
https://ncbi.nlm.nih.gov/pubmed/29304076
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0190864
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