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NMDA- and β-Amyloid(1–42)-Induced Neurotoxicity Is Attenuated in Serine Racemase Knock-Out Mice
d-Serine is detected in the brain and acts as a coagonist at the “glycine-site” of the NMDA-type glutamate receptor. Although d-serine can be directly produced from l-serine by serine racemase (SR), the relative contribution of SR in d-serine formation in vivo is not known. Pathological roles of bra...
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| 出版年: | J Neurosci |
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| 主要な著者: | , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Society for Neuroscience
2008
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6671248/ https://ncbi.nlm.nih.gov/pubmed/19118183 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.5034-08.2008 |
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