Chloroquine reduces hypercoagulability in pancreatic cancer through inhibition of neutrophil extracellular traps

BACKGROUND: The hypercoagulable state associated with pancreatic adenocarcinoma (PDA) results in increased risk of venous thromboembolism, leading to substantial morbidity and mortality. Recently, neutrophil extracellular traps (NETs), whereby activated neutrophils release their intracellular conten...

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Dades bibliogràfiques
Publicat a:BMC Cancer
Autors principals: Boone, Brian A., Murthy, Pranav, Miller-Ocuin, Jennifer, Doerfler, W. Reed, Ellis, Jarrod T., Liang, Xiaoyan, Ross, Mark A., Wallace, Callen T., Sperry, Jason L., Lotze, Michael T., Neal, Matthew D., Zeh, Herbert J.
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2018
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6013899/
https://ncbi.nlm.nih.gov/pubmed/29929491
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-018-4584-2
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