Chloroquine reduces hypercoagulability in pancreatic cancer through inhibition of neutrophil extracellular traps

BACKGROUND: The hypercoagulable state associated with pancreatic adenocarcinoma (PDA) results in increased risk of venous thromboembolism, leading to substantial morbidity and mortality. Recently, neutrophil extracellular traps (NETs), whereby activated neutrophils release their intracellular conten...

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Detalhes bibliográficos
Publicado no:BMC Cancer
Main Authors: Boone, Brian A., Murthy, Pranav, Miller-Ocuin, Jennifer, Doerfler, W. Reed, Ellis, Jarrod T., Liang, Xiaoyan, Ross, Mark A., Wallace, Callen T., Sperry, Jason L., Lotze, Michael T., Neal, Matthew D., Zeh, Herbert J.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2018
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6013899/
https://ncbi.nlm.nih.gov/pubmed/29929491
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-018-4584-2
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