Chloroquine reduces hypercoagulability in pancreatic cancer through inhibition of neutrophil extracellular traps

BACKGROUND: The hypercoagulable state associated with pancreatic adenocarcinoma (PDA) results in increased risk of venous thromboembolism, leading to substantial morbidity and mortality. Recently, neutrophil extracellular traps (NETs), whereby activated neutrophils release their intracellular conten...

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Bibliografiske detaljer
Udgivet i:BMC Cancer
Main Authors: Boone, Brian A., Murthy, Pranav, Miller-Ocuin, Jennifer, Doerfler, W. Reed, Ellis, Jarrod T., Liang, Xiaoyan, Ross, Mark A., Wallace, Callen T., Sperry, Jason L., Lotze, Michael T., Neal, Matthew D., Zeh, Herbert J.
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2018
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6013899/
https://ncbi.nlm.nih.gov/pubmed/29929491
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-018-4584-2
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