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Conformational Selection in the Recognition of the Snurportin Importin β Binding Domain by Importin β()

The structural flexibility of β-karyopherins is critical to mediate the interaction with transport substrates, nucleoporins, and the GTPase Ran. In this paper, we provide structural evidence that the molecular recognition of the transport adaptor snurportin by importin β follows the population selec...

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Bibliographic Details
Published in:Biochemistry
Main Authors: Bhardwaj, Anshul, Cingolani, Gino
Format: Artigo
Language:Inglês
Published: 2010
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6013741/
https://ncbi.nlm.nih.gov/pubmed/20476751
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi100292y
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