DIPG-77. INTRATUMORAL PHARMACOKINETICS OF CHEMOTHERAPY IN DIPG: XENOGRAFT AND INITIAL PHASE 0 CLINICAL TRIAL RESULTS

INTRODUCTION: Hundreds of chemotherapy trials have been conducted in diffuse intrinsic pontine glioma (DIPG) without survival improvement. One potential reason is a lack of intratumoral penetration, but this has not previously been assessed in humans. We used gemcitabine as a model agent to assess D...

Descripción completa

Guardado en:
Detalles Bibliográficos
Publicado en:Neuro Oncol
Autores principales: Green, Adam, Flannery, Patrick, Hankinson, Todd, O’Neill, Brent, DeSisto, John, Lemma, Rakeb, Hoffman, Lindsey, Levy, Jean Mulcahy, Raybin, Jennifer, Hemenway, Molly, Koschmann, Carl, Handler, Michael, Foreman, Nicholas, Vibhakar, Rajeev, Wempe, Michael, Dorris, Kathleen
Formato: Artigo
Lenguaje:Inglês
Publicado: Oxford University Press 2018
Materias:
Abstracts
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6012608/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noy059.169
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares