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DIPG-77. INTRATUMORAL PHARMACOKINETICS OF CHEMOTHERAPY IN DIPG: XENOGRAFT AND INITIAL PHASE 0 CLINICAL TRIAL RESULTS
INTRODUCTION: Hundreds of chemotherapy trials have been conducted in diffuse intrinsic pontine glioma (DIPG) without survival improvement. One potential reason is a lack of intratumoral penetration, but this has not previously been assessed in humans. We used gemcitabine as a model agent to assess D...
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| Wydane w: | Neuro Oncol |
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| Główni autorzy: | , , , , , , , , , , , , , , , |
| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
Oxford University Press
2018
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6012608/ https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noy059.169 |
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