QOL-53. METFORMIN RESULTS IN HIPPOCAMPAL REMODELING AND IMPROVED MEMORY ENCODING IN PAEDIATRIC BRAIN TUMOR SURVIVORS TREATED WITH CRANIAL RADIATION: A PILOT RANDOMIZED CONTROLLED CROSSOVER STUDY

OBJECTIVES: Although curative, cranial radiation results in hippocampal insult and memory impairment in children with brain tumours. Metformin stimulates hippocampal neurogenesis and improves memory performance in mice. We conducted a pilot double-blind randomized controlled cross-over trial to exam...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Neuro Oncol
Main Authors: Ayoub, Ramy, Miller, Freda, Beera, Kiran, de Medeiros, Cynthia, Laughlin, Suzanne, Bouffet, Eric, Mabbott, Donald
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2018
Assuntos:
Abstracts
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6012547/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noy059.634
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados