MBRS-36. IDENTIFICATION OF TWO PROTEIN-SIGNALING STATES DELINEATING TRANSCRIPTIONALLY HETEROGENEOUS HUMAN MEDULLOBLASTOMA

Medulloblastoma consists of different transcriptional subgroups. To characterize medulloblastoma at the phosphoprotein-signaling level, we performed high-throughput peptide phosphorylation profiling on a cohort of SHH, Group 3 and Group 4 medulloblastomas. We identified two major protein-signaling p...

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Publicado no:Neuro Oncol
Main Authors: Zomerman, Walderik, Plasschaert, Sabine, Conroy, Siobhan, Scherpen, Frank, Boer, Tiny Meeuwsen-de, Lourens, Harm-Jan, Llobet, Sergi Guerrero, Smit, Marlinde, Slagter-Menkema, Lorian, Seitz, Annika, Gidding, Corrie, Hulleman, Esther, Wesseling, Pieter, Meijer, Lisethe, van Kempen, Leon, van den Berg, Anke, Warmerdam, Daniel, Kruyt, Frank, Foijer, Floris, van Vugt, Marcel, den Dunnen, Wilfred, Hoving, Eelco, Guryev, Victor, de Bont, Eveline, Bruggeman, Sophia
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6012173/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noy059.481
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