MBCL-44. THE MOLECULAR AND CLINICAL LANDSCAPE OF INFANT MEDULLOBLASTOMA (iMB): RESULTS AND MOLECULAR ANALYSIS FROM A PROSPECTIVE, MULTICENTER PHASE II TRIAL (SJYC07)

BACKGROUND: iMB has inferior survival to older children principally due to radiation-sparing therapy. To better understand which patients may benefit from radiation-sparing protocols, we describe the molecular landscape of iMB and report the iMB outcome on the SJYC07 trial designed to defer, reduce,...

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Publicado en:Neuro Oncol
Autores principales: Robinson, Giles W, Rudneva, Vasilisa A, Buchhalter, Ivo, Billups, Catherine A, Waszak, Sebastian M, Smith, Kyle, Bowers, Daniel C, Bendel, Anne, Fisher, Paul, Partap, Sonia, Crawford, John, Hassall, Tim, Indelicato, Daniel J, Boop, Frederick, Klimo, Paul, Sabin, Noah D, Patay, Zoltan, Merchant, Thomas E, Stewart, Clinton F, Orr, Brent A, Korbel, Jan O, Jones, David T W, Sharma, Tanvi, Lichter, Peter, Kool, Marcel, Korshunov, Andrey, Pfister, Stefan M, Gilbertson, Richard J, Sanders, Robert P, Onar-Thomas, Arzu, Ellison, David W, Gajjar, Amar, Northcott, Paul A
Formato: Artigo
Lenguaje:Inglês
Publicado: Oxford University Press 2018
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6012030/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noy059.440
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