RISK-ADAPTED THERAPY AND BIOLOGICAL HETEROGENEITY IN PINEOBLASTOMA: INTEGRATED CLINICO-PATHOLOGICAL ANALYSIS FROM THE PROSPECTIVE, MULTI-CENTER SJMB03 AND SJYC07 TRIALS

Pineoblastoma is a rare embryonal tumor of childhood that is conventionally treated with high-dose craniospinal irradiation (CSI). Multi-dimensional molecular evaluation of pineoblastoma and associated intertumoral heterogeneity is lacking. Herein, we report outcomes and molecular features of childr...

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Bibliografiska uppgifter
I publikationen:Acta Neuropathol
Huvudupphovsmän: Liu, Anthony P.Y., Gudenas, Brian, Lin, Tong, Orr, Brent A., Klimo, Paul, Kumar, Rahul, Bouffet, Eric, Gururangan, Sridharan, Crawford, John R., Kellie, Stewart J., Chintagumpala, Murali, Fisher, Michael J., Bowers, Daniel C., Hassall, Tim, Indelicato, Daniel J., Onar-Thomas, Arzu, Ellison, David W., Boop, Frederick A., Merchant, Thomas E., Robinson, Giles W., Northcott, Paul A., Gajjar, Amar
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2019
Ämnen:
Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC7065912/
https://ncbi.nlm.nih.gov/pubmed/31802236
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00401-019-02106-9
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