RISK-ADAPTED THERAPY AND BIOLOGICAL HETEROGENEITY IN PINEOBLASTOMA: INTEGRATED CLINICO-PATHOLOGICAL ANALYSIS FROM THE PROSPECTIVE, MULTI-CENTER SJMB03 AND SJYC07 TRIALS

Pineoblastoma is a rare embryonal tumor of childhood that is conventionally treated with high-dose craniospinal irradiation (CSI). Multi-dimensional molecular evaluation of pineoblastoma and associated intertumoral heterogeneity is lacking. Herein, we report outcomes and molecular features of childr...

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Detalhes bibliográficos
Publicado no:Acta Neuropathol
Main Authors: Liu, Anthony P.Y., Gudenas, Brian, Lin, Tong, Orr, Brent A., Klimo, Paul, Kumar, Rahul, Bouffet, Eric, Gururangan, Sridharan, Crawford, John R., Kellie, Stewart J., Chintagumpala, Murali, Fisher, Michael J., Bowers, Daniel C., Hassall, Tim, Indelicato, Daniel J., Onar-Thomas, Arzu, Ellison, David W., Boop, Frederick A., Merchant, Thomas E., Robinson, Giles W., Northcott, Paul A., Gajjar, Amar
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7065912/
https://ncbi.nlm.nih.gov/pubmed/31802236
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00401-019-02106-9
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