LGG-13. RESOLVING TRANSCRIPTIONAL PROFILES IN BRAF-REARRANGED PILOCYTIC ASTROCYTOMA USING SINGLE CELL RNA SEQUENCING

Pilocytic astrocytoma (PAs) are pediatric low grade gliomas that frequently harbor oncogenic KIAA1549-BRAF fusions and exhibit low rates of other somatic genetic alterations. Previous transcriptomic profiling of bulk PA tissues sought to uncover gene expression programs that distinguish PA from othe...

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Published in:Neuro Oncol
Main Authors: Reitman, Zachary, Paolella, Brenton, Bergthold, Guillaume, Pelton, Kristine, Becker, Sarah, Jones, Robert, Herbert, Zach, Grimmett, Leslie, Daley, John, Filbin, Mariella, Suva, Mario, Goumnerova, Liliana, Wright, Karen, Chi, Susan, Kieran, Mark, Regev, Aviv, Shalek, Alex, Ligon, Keith L, Beroukhim, Rameen, Bandopadhayay, Pratiti
Format: Artigo
Language:Inglês
Published: Oxford University Press 2018
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6011968/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noy059.355
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