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FKBP12.6 protects heart from AngII‐induced hypertrophy through inhibiting Ca(2+)/calmodulin‐mediated signalling pathways in vivo and in vitro
We previously observed that disruption of FK506‐binding protein 12.6 (FKBP12.6) gene resulted in cardiac hypertrophy in male mice. Studies showed that overexpression of FKBP12.6 attenuated thoracic aortic constriction (TAC)‐induced cardiac hypertrophy in mice, whereas the adenovirus‐mediated overexp...
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| Publicado no: | J Cell Mol Med |
|---|---|
| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
John Wiley and Sons Inc.
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6010737/ https://ncbi.nlm.nih.gov/pubmed/29682889 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.13645 |
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