Učitavanje...
Human IgM antibody rHIgM22 promotes phagocytic clearance of myelin debris by microglia
In multiple sclerosis (MS), demyelinated CNS lesions fail to sufficiently remyelinate, despite the presence of oligodendrocyte precursor cells (OPCs) capable of differentiating into mature oligodendrocytes. MS lesions contain damaged myelin debris that can inhibit OPC maturation and hinder repair. r...
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| Izdano u: | Sci Rep |
|---|---|
| Glavni autori: | , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Nature Publishing Group UK
2018
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6010437/ https://ncbi.nlm.nih.gov/pubmed/29925848 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-27559-y |
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