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Formation of supramolecular activation clusters on fresh ex vivo CD8(+) T cells after engagement of the T cell antigen receptor and CD8 by antigen-presenting cells
Upon productive interaction of CD4 T cells with antigen-presenting cells (APCs), receptors and intracellular proteins translocate and form spatially segregated supramolecular activation clusters (SMACs). It is not known whether SMACs are required for CD8 T cell activation. CD8 T cells, unlike CD4 T...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The National Academy of Sciences
2001
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC60104/ https://ncbi.nlm.nih.gov/pubmed/11606747 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.221458898 |
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