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Cognate antigen engagement on parenchymal cells stimulates CD8(+) T cell proliferation in situ

T-cell responses are initiated upon cognate presentation by professional antigen presenting cells in lymphoid tissue. T cells then migrate to inflamed tissues, but further T-cell stimulation in these parenchymal target sites is not well understood. Here we show that T-cell expansion within inflamed...

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Bibliografiska uppgifter
I publikationen:Nat Commun
Huvudupphovsmän: Sutherland, Robyn M., Londrigan, Sarah L., Brady, Jamie L., Carrington, Emma M., Marchingo, Julia M., Heinzel, Susanne, Hodgkin, Philip D., Graham, Kate L., Kay, Thomas W., Zhan, Yifan, Lew, Andrew M.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Nature Publishing Group 2017
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5394288/
https://ncbi.nlm.nih.gov/pubmed/28401883
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms14809
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