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Molecular anatomy of antigen-specific CD8(+) T cell engagement and synapse formation in vivo

Antigen-specific CD8(+) T cells are required for the clearance of most viral infections and several cancers. However, it is not clear in vivo whether CD8(+) T cells can engage multiple targets simultaneously, engagement results in the formation of an immunologic synapse or molecules involved in CD8...

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Detalhes bibliográficos
Main Authors: McGavern, Dorian B., Christen, Urs, Oldstone, Michael B.A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2481514/
https://ncbi.nlm.nih.gov/pubmed/12352968
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ni843
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