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Integrating Experimental and In Silico HTS in the Discovery of Inhibitors of Protein Nucleic Acid Interactions

Discovery of novel tool compounds and drug leads against a range of unorthodox protein targets has pushed both experimental screening methodologies as well as the field of structure based design to the limit in recent years. Increasingly, it has been recognized that some of the most desirable target...

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Salvato in:
Dettagli Bibliografici
Pubblicato in:Methods Enzymol
Autori principali: Li, Quinn, Constantino, Laura Folly da Silva, Spies, M. Ashley
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2018
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6010167/
https://ncbi.nlm.nih.gov/pubmed/29523234
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/bs.mie.2017.11.036
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