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Development of a HTS-Compatible Assay for the Discovery of Ulk1 Inhibitors

A rapidly accumulating body of work suggests the autophagy pathway is an attractive therapeutic target for neurodegenerative diseases and cancer. To validate autophagy as an anticancer strategy and to assess if systemic inhibition of the pathway will have deleterious effects on normal tissues and ph...

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Pubblicato in:J Biomol Screen
Autori principali: Rosenberg, Laura H., Lafitte, Marie, Grant, Wayne, Chen, Weimin, Cleveland, John L., Duckett, Derek R.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4744088/
https://ncbi.nlm.nih.gov/pubmed/25851035
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1087057115579391
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