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Integrating Experimental and In Silico HTS in the Discovery of Inhibitors of Protein Nucleic Acid Interactions

Discovery of novel tool compounds and drug leads against a range of unorthodox protein targets has pushed both experimental screening methodologies as well as the field of structure based design to the limit in recent years. Increasingly, it has been recognized that some of the most desirable target...

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Bibliografiske detaljer
Udgivet i:Methods Enzymol
Main Authors: Li, Quinn, Constantino, Laura Folly da Silva, Spies, M. Ashley
Format: Artigo
Sprog:Inglês
Udgivet: 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6010167/
https://ncbi.nlm.nih.gov/pubmed/29523234
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/bs.mie.2017.11.036
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