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Isatin: a privileged scaffold for the design of carbonic anhydrase inhibitors

The isatin scaffold is the constitutive fragment of several natural and synthetic bioactive molecules. Albeit several benzene sulphonamide-based carbonic anhydrase inhibitors (CAIs) have been reported, only recently isatin benzene sulphonamides have been studied and proposed as CAIs. In this study w...

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Bibliographic Details
Published in:J Enzyme Inhib Med Chem
Main Authors: Melis, Claudia, Meleddu, Rita, Angeli, Andrea, Distinto, Simona, Bianco, Giulia, Capasso, Clemente, Cottiglia, Filippo, Angius, Rossella, Supuran, Claudiu T., Maccioni, Elias
Format: Artigo
Language:Inglês
Published: Taylor & Francis 2016
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6010117/
https://ncbi.nlm.nih.gov/pubmed/27775452
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/14756366.2016.1235042
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