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Zinc binding groups for histone deacetylase inhibitors
Zinc binding groups (ZBGs) play a crucial role in targeting histone deacetylase inhibitors (HDACIs) to the active site of histone deacetylases (HDACs), thus determining the potency of HDACIs. Due to the high affinity to the zinc ion, hydroxamic acid is the most commonly used ZBG in the structure of...
में बचाया:
| में प्रकाशित: | J Enzyme Inhib Med Chem |
|---|---|
| मुख्य लेखकों: | , , , , |
| स्वरूप: | Artigo |
| भाषा: | Inglês |
| प्रकाशित: |
Taylor & Francis
2018
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| विषय: | |
| ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6009916/ https://ncbi.nlm.nih.gov/pubmed/29616828 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/14756366.2017.1417274 |
| टैग : |
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