N-aryl 2-aryloxyacetamides as a new class of fatty acid amide hydrolase (FAAH) inhibitors

Fatty acid amide hydrolase (FAAH) is a promising target for the development of drugs to treat neurological diseases. In search of new FAAH inhibitors, we identified 2-(4-cyclohexylphenoxy)-N-(3-(oxazolo[4,5-b]pyridin-2-yl)phenyl)acetamide, 4g, with an IC(50) of 2.6 µM as a chemical starting point fo...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:J Enzyme Inhib Med Chem
Main Authors: Sunduru, Naresh, Svensson, Mona, Cipriano, Mariateresa, Marwaha, Sania, Andersson, C. David, Svensson, Richard, Fowler, Christopher J., Elofsson, Mikael
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis 2017
Fag:
Short Communication
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6009913/
https://ncbi.nlm.nih.gov/pubmed/28114819
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/14756366.2016.1265520
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker