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Novel series of 1,2,4-trioxane derivatives as antimalarial agents

Among three series of 1,2,4-trioxane derivatives, five compounds showed good in vitro antimalarial activity, three compounds of which exhibited better activity against P. falciparum resistant (RKL9) strain than the sensitive (3D7) one. Two best compounds were one from aryl series and the other from...

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Dades bibliogràfiques
Publicat a:J Enzyme Inhib Med Chem
Autors principals: Rudrapal, Mithun, Chetia, Dipak, Singh, Vineeta
Format: Artigo
Idioma:Inglês
Publicat: Taylor & Francis 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6009891/
https://ncbi.nlm.nih.gov/pubmed/28870093
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/14756366.2017.1363742
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