A Novel Series of [1,2,4]Triazolo[4,3-a]Pyridine Sulfonamides as Potential Antimalarial Agents: In Silico Studies, Synthesis and In Vitro Evaluation

For the development of new and potent antimalarial drugs, we designed the virtual library with three points of randomization of novel [1,2,4]triazolo[4,3-a]pyridines bearing a sulfonamide fragment. The library of 1561 compounds has been investigated by both virtual screening and molecular docking me...

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Veröffentlicht in:Molecules
Hauptverfasser: Karpina, Veronika R., Kovalenko, Svitlana S., Kovalenko, Sergiy M., Drushlyak, Oleksandr G., Bunyatyan, Natalya D., Georgiyants, Victoriya A., Ivanov, Vladimir V., Langer, Thierry, Maes, Louis
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2020
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7582516/
https://ncbi.nlm.nih.gov/pubmed/33007887
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules25194485
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