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Novel series of 1,2,4-trioxane derivatives as antimalarial agents

Among three series of 1,2,4-trioxane derivatives, five compounds showed good in vitro antimalarial activity, three compounds of which exhibited better activity against P. falciparum resistant (RKL9) strain than the sensitive (3D7) one. Two best compounds were one from aryl series and the other from...

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Detalhes bibliográficos
Publicado no:J Enzyme Inhib Med Chem
Main Authors: Rudrapal, Mithun, Chetia, Dipak, Singh, Vineeta
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6009891/
https://ncbi.nlm.nih.gov/pubmed/28870093
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/14756366.2017.1363742
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