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Novel series of 1,2,4-trioxane derivatives as antimalarial agents

Among three series of 1,2,4-trioxane derivatives, five compounds showed good in vitro antimalarial activity, three compounds of which exhibited better activity against P. falciparum resistant (RKL9) strain than the sensitive (3D7) one. Two best compounds were one from aryl series and the other from...

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Библиографические подробности
Опубликовано в: :J Enzyme Inhib Med Chem
Главные авторы: Rudrapal, Mithun, Chetia, Dipak, Singh, Vineeta
Формат: Artigo
Язык:Inglês
Опубликовано: Taylor & Francis 2017
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6009891/
https://ncbi.nlm.nih.gov/pubmed/28870093
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/14756366.2017.1363742
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