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Exhaustive CoMFA and CoMSIA analyses around different chemical entities: a ligand-based study exploring the affinity and selectivity profiles of 5-HT(1A) ligands
The 5-hydroxytryptamine (5-HT(1A)) receptors represent an attractive target in drug discovery. In particular, 5-HT(1A) agonists and partial agonists are deeply investigated for their potential role in the treatment of anxiety, depression, ischaemic brain disorder and more recently, of pain. On the o...
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| Publicado en: | J Enzyme Inhib Med Chem |
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| Autores principales: | , , , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Taylor & Francis
2017
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6009877/ https://ncbi.nlm.nih.gov/pubmed/28114832 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/14756366.2016.1247057 |
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