CoMFA and CoMSIA Studies of 1,2-dihydropyridine Derivatives as Anticancer Agents

Taking advantage of our in-house experimental data on 3-cyano-2-imino-1, 2-dihydropyridine and 3-cyano-2-oxo-1,2-dihydropyridine derivatives as inhibitors of the growth of the human HT-29 colon adenocarcinoma tumor cell line, we have established a highly significant CoMFA and CoMSIA models (q(2)(cv)...

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Bibliografiske detaljer
Udgivet i:Med Chem
Main Authors: Salama, Ismail, Abdel-Fattah, Mohamed A. O., Hany, Marwa S., El-Sharif, Shaimaa A., El-Naggar, Mahmoud A. M., Rashied, Rasha M. H., Piazza, Gary A., Abadi, Ashraf H.
Format: Artigo
Sprog:Inglês
Udgivet: 2012
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4980841/
https://ncbi.nlm.nih.gov/pubmed/22530888
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