CoMFA, CoMSIA and Eigenvalue Analysis on Dibenzodioxepinone and Dibenzodioxocinone Derivatives as Cholesteryl Ester Transfer Protein Inhibitors

CoMFA, CoMSIA and eigenvalue analysis (EVA) were performed to study the structural features of 61 diverse dibenzodioxepinone and dibenzodioxocinone analogues to probe cholesteryl ester transfer protein (CETP) inhibitory activity. Three methods yielded statistically significant models upon assessment...

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Vydáno v:Molecules
Hlavní autoři: Xiong, Xu-qiong, Zhao, Dong-mei, Bu, Peng-fei, Liu, Yang, Ren, Jin-hong, Wang, Jian, Cheng, Mao-sheng
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2008
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6245342/
https://ncbi.nlm.nih.gov/pubmed/18794787
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules13081822
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