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Blockade of LOX-1 Prevents Endotoxin-Induced Acute Lung Inflammation and Injury in Mice

Lectin-like oxidized low-density lipoprotein (LDL) receptor-1 (LOX-1), a cell surface receptor expressed in endothelial cells, is known to mediate oxidized LDL-induced vascular inflammation and atherogenesis. Although the role of LOX-1 in vascular inflammation has been well established, its involvem...

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Bibliographic Details
Published in:J Innate Immun
Main Authors: Zhang, Ping, Liu, Ming-Cheh, Cheng, Lili, Liang, Mei, Ji, Hong-long, Fu, Jian
Format: Artigo
Language:Inglês
Published: 2008
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6009841/
https://ncbi.nlm.nih.gov/pubmed/20375593
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000161070
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