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LOX-1 Deletion Improves Neutrophil Responses, Enhances Bacterial Clearance, and Reduces Lung Injury in a Murine Polymicrobial Sepsis Model

Inflammatory tissue injury and immunosuppression are the major causes of death in sepsis. Novel therapeutic targets that can prevent excessive inflammation and improve immune responses during sepsis could be critical for treatment of this devastating disease. LOX-1 (lectin-like oxidized low-density...

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Detalhes bibliográficos
Main Authors: Wu, Zhuang, Sawamura, Tatsuya, Kurdowska, Anna K., Ji, Hong-Long, Idell, Steven, Fu, Jian
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3191957/
https://ncbi.nlm.nih.gov/pubmed/21576343
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.01317-10
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