RvE1 Attenuates Polymicrobial Sepsis-Induced Cardiac Dysfunction and Enhances Bacterial Clearance

The development of cardiac dysfunction caused by microbial infection predicts high mortality in sepsis patients. Specialized pro-resolving mediators (SPMs) mediate resolution of inflammation in many inflammatory diseases, and are differentially expressed in plasma of sepsis patients. Here, we invest...

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Detalhes bibliográficos
Main Authors: Jianmin Chen, Gareth S. D. Purvis, Debora Collotta, Sura Al Zoubi, Michelle A. Sugimoto, Antonino Cacace, Lukas Martin, Roman A. Colas, Massimo Collino, Jesmond Dalli, Christoph Thiemermann
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020-09-01
Colecção:Frontiers in Immunology
Assuntos:
polymicrobial sepsis
resolvin E1
bacterial clearance
immune response
cardiomyopathy
Acesso em linha:https://www.frontiersin.org/article/10.3389/fimmu.2020.02080/full
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