Detrimental Role of CC Chemokine Receptor 4 in Murine Polymicrobial Sepsis

CC chemokine receptor 4 (CCR4) and its two ligands, CCL17 and CCL22, are critically involved in different immune processes. In models of lipopolysaccharide-induced shock, CCR4-deficient (CCR4(−/−)) mice showed improved survival rates associated with attenuated proinflammatory cytokine release. Using...

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Detalhes bibliográficos
Main Authors: Traeger, Tobias, Kessler, Wolfram, Assfalg, Volker, Cziupka, Katharina, Koerner, Pia, Dassow, Constanze, Breitbach, Katrin, Mikulcak, Marlene, Steinmetz, Ivo, Pfeffer, Klaus, Heidecke, Claus-Dieter, Maier, Stefan
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2008
Assuntos:
Host Response and Inflammation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2573314/
https://ncbi.nlm.nih.gov/pubmed/18765730
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00310-08
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