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New insights into the interplay between the translation machinery and nonsense-mediated mRNA decay factors
Faulty mRNAs with a premature stop codon (PTC) are recognized and degraded by nonsense-mediated mRNA decay (NMD). Recognition of a nonsense mRNA depends on translation and on the presence of NMD-enhancing or the absence of NMD-inhibiting factors in the 3′-untranslated region. Our review summarizes o...
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| Publicado no: | Biochem Soc Trans |
|---|---|
| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Portland Press Ltd.
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6008592/ https://ncbi.nlm.nih.gov/pubmed/29626148 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BST20170427 |
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