Biological and Pathological Implications of an Alternative ATP-Powered Proteasomal Assembly With Cdc48 and the 20S Peptidase

The ATP-powered protein degradation machinery plays essential roles in maintaining protein homeostasis in all organisms. Robust proteolytic activities are typically sequestered within protein complexes to avoid the fatal removal of essential proteins. Because the openings of proteolytic chambers are...

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Bibliographic Details
Published in:Front Mol Biosci
Main Authors: Esaki, Masatoshi, Johjima-Murata, Ai, Islam, Md. Tanvir, Ogura, Teru
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2018
Subjects:
Molecular Biosciences
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6008533/
https://ncbi.nlm.nih.gov/pubmed/29951484
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmolb.2018.00056
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