Biological and Pathological Implications of an Alternative ATP-Powered Proteasomal Assembly With Cdc48 and the 20S Peptidase

The ATP-powered protein degradation machinery plays essential roles in maintaining protein homeostasis in all organisms. Robust proteolytic activities are typically sequestered within protein complexes to avoid the fatal removal of essential proteins. Because the openings of proteolytic chambers are...

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Vydáno v:Front Mol Biosci
Hlavní autoři: Esaki, Masatoshi, Johjima-Murata, Ai, Islam, Md. Tanvir, Ogura, Teru
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2018
Témata:
Molecular Biosciences
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6008533/
https://ncbi.nlm.nih.gov/pubmed/29951484
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmolb.2018.00056
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