Biological and Pathological Implications of an Alternative ATP-Powered Proteasomal Assembly With Cdc48 and the 20S Peptidase

The ATP-powered protein degradation machinery plays essential roles in maintaining protein homeostasis in all organisms. Robust proteolytic activities are typically sequestered within protein complexes to avoid the fatal removal of essential proteins. Because the openings of proteolytic chambers are...

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Detalhes bibliográficos
Publicado no:Front Mol Biosci
Main Authors: Esaki, Masatoshi, Johjima-Murata, Ai, Islam, Md. Tanvir, Ogura, Teru
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018
Assuntos:
Molecular Biosciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6008533/
https://ncbi.nlm.nih.gov/pubmed/29951484
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmolb.2018.00056
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