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Deviation of the typical AAA substrate-threading pore prevents fatal protein degradation in yeast Cdc48

Yeast Cdc48 is a well-conserved, essential chaperone of ATPases associated with diverse cellular activity (AAA) proteins, which recognizes substrate proteins and modulates their conformations to carry out many cellular processes. However, the fundamental mechanisms underlying the diverse pivotal rol...

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Détails bibliographiques
Publié dans:Sci Rep
Auteurs principaux: Esaki, Masatoshi, Islam, Md. Tanvir, Tani, Naoki, Ogura, Teru
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group UK 2017
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5511170/
https://ncbi.nlm.nih.gov/pubmed/28710470
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-05806-y
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