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Deviation of the typical AAA substrate-threading pore prevents fatal protein degradation in yeast Cdc48

Yeast Cdc48 is a well-conserved, essential chaperone of ATPases associated with diverse cellular activity (AAA) proteins, which recognizes substrate proteins and modulates their conformations to carry out many cellular processes. However, the fundamental mechanisms underlying the diverse pivotal rol...

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Bibliografiske detaljer
Udgivet i:Sci Rep
Main Authors: Esaki, Masatoshi, Islam, Md. Tanvir, Tani, Naoki, Ogura, Teru
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5511170/
https://ncbi.nlm.nih.gov/pubmed/28710470
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-05806-y
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