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Positive Cooperativity of the p97 AAA ATPase Is Critical for Essential Functions
p97 is composed of two conserved AAA (ATPases associated with diverse cellular activities) domains, which form a tandem hexameric ring. We characterized the ATP hydrolysis mechanism of CDC-48.1, a p97 homolog of Caenorhabditis elegans. The ATPase activity of the N-terminal AAA domain was very low at...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3091191/ https://ncbi.nlm.nih.gov/pubmed/21454554 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.201400 |
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