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The Thrombin Receptor Restricts Subventricular Zone Neural Stem Cell Expansion and Differentiation
Thrombin is frequently increased in the CNS after injury yet little is known regarding its effects on neural stem cells. Here we show that the subventricular zone (SVZ) of adult mice lacking the high affinity receptor for thrombin, proteinase activated receptor 1 (PAR1), show increased numbers of So...
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| Publicado no: | Sci Rep |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6008392/ https://ncbi.nlm.nih.gov/pubmed/29921916 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-27613-9 |
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