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Structural basis for antibody-mediated neutralization of Lassa virus
The arenavirus Lassa causes severe hemorrhagic fever and a significant disease burden in West Africa every year. The glycoprotein, GPC, is the sole antigen expressed on the viral surface and the critical target for antibody-mediated neutralization. Here we present the crystal structure of the trimer...
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| Publicado no: | Science |
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| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6007842/ https://ncbi.nlm.nih.gov/pubmed/28572385 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.aam7260 |
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