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Structural Basis for the dsRNA Specificity of the Lassa Virus NP Exonuclease
Lassa virus causes hemorrhagic fever characterized by immunosuppression. The nucleoprotein of Lassa virus, termed NP, binds the viral genome. It also has an additional enzymatic activity as an exonuclease that specifically digests double-stranded RNA (dsRNA). dsRNA is a strong signal to the innate i...
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| Główni autorzy: | , , , |
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| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
Public Library of Science
2012
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3429428/ https://ncbi.nlm.nih.gov/pubmed/22937163 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0044211 |
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