Telomere sequence content can be used to determine ALT activity in tumours

The replicative immortality of human cancer cells is achieved by activation of a telomere maintenance mechanism (TMM). To achieve this, cancer cells utilise either the enzyme telomerase, or the Alternative Lengthening of Telomeres (ALT) pathway. These distinct molecular pathways are incompletely und...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Main Authors: Lee, Michael, Teber, Erdahl T, Holmes, Oliver, Nones, Katia, Patch, Ann-Marie, Dagg, Rebecca A, Lau, Loretta M S, Lee, Joyce H, Napier, Christine E, Arthur, Jonathan W, Grimmond, Sean M, Hayward, Nicholas K, Johansson, Peter A, Mann, Graham J, Scolyer, Richard A, Wilmott, James S, Reddel, Roger R, Pearson, John V, Waddell, Nicola, Pickett, Hilda A
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2018
Assuntos:
Computational Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6007693/
https://ncbi.nlm.nih.gov/pubmed/29718321
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gky297
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados