Variant repeats are interspersed throughout the telomeres and recruit nuclear receptors in ALT cells

Telomeres in cells that use the recombination-mediated alternative lengthening of telomeres (ALT) pathway elicit a DNA damage response that is partly independent of telomere length. We therefore investigated whether ALT telomeres contain structural abnormalities that contribute to ALT activity. Here...

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Autors principals: Conomos, Dimitri, Stutz, Michael D., Hills, Mark, Neumann, Axel A., Bryan, Tracy M., Reddel, Roger R., Pickett, Hilda A.
Format: Artigo
Idioma:Inglês
Publicat: The Rockefeller University Press 2012
Matèries:
Research Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3518223/
https://ncbi.nlm.nih.gov/pubmed/23229897
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201207189
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