The DNA damage response activates HPV16 late gene expression at the level of RNA processing

We show that the alkylating cancer drug melphalan activated the DNA damage response and induced human papillomavirus type 16 (HPV16) late gene expression in an ATM- and Chk1/2-dependent manner. Activation of HPV16 late gene expression included inhibition of the HPV16 early polyadenylation signal tha...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Main Authors: Nilsson, Kersti, Wu, Chengjun, Kajitani, Naoko, Yu, Haoran, Tsimtsirakis, Efthymios, Gong, Lijing, Winquist, Ellenor B, Glahder, Jacob, Ekblad, Lars, Wennerberg, Johan, Schwartz, Stefan
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2018
Assuntos:
Genome Integrity, Repair and Replication
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6007495/
https://ncbi.nlm.nih.gov/pubmed/29596642
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gky227
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