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LRP/LR specific antibody IgG1-iS18 impedes neurodegeneration in Alzheimer's disease mice
Alzheimer’s disease (AD) is a neurodegenerative disease caused by accumulation of amyloid beta (Aβ) plaque and neurofibrillary tangle formation. We have shown in vitro, that knock-down and blockade of the 37 kDa/67 kDa Laminin Receptor (LRP/LR) resulted in reduced Aβ induced cytotoxicity and Aβ accu...
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| Publicado no: | Oncotarget |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Impact Journals LLC
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6007457/ https://ncbi.nlm.nih.gov/pubmed/29930750 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.25473 |
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