Knock-Down of the 37kDa/67kDa Laminin Receptor LRP/LR Impedes Telomerase Activity

Cancer has become a major problem worldwide due to its increasing incidence and mortality rates. Both the 37kDa/67kDa laminin receptor (LRP/LR) and telomerase are overexpressed in cancer cells. LRP/LR enhances the invasiveness of cancer cells thereby promoting metastasis, supporting angiogenesis and...

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Veröffentlicht in:PLoS One
Hauptverfasser: Naidoo, Kerrilyn, Malindisa, Sibusiso T., Otgaar, Tyrone C., Bernert, Martin, Da Costa Dias, Bianca, Ferreira, Eloise, Reusch, Uwe, Knackmuss, Stefan, Little, Melvyn, Weiss, Stefan F. T., Letsolo, Boitelo T.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2015
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Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4636255/
https://ncbi.nlm.nih.gov/pubmed/26545108
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0141618
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