The 37kDa/67kDa Laminin Receptor acts as a receptor for Aβ(42) internalization

Neuronal loss is a major neuropathological hallmark of Alzheimer's disease (AD). The associations between soluble Aβ oligomers and cellular components cause this neurotoxicity. The 37 kDa/67 kDa laminin receptor (LRP/LR) has recently been implicated in Aβ pathogenesis. In this study the mechani...

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Detalhes bibliográficos
Main Authors: Da Costa Dias, Bianca, Jovanovic, Katarina, Gonsalves, Danielle, Moodley, Kiashanee, Reusch, Uwe, Knackmuss, Stefan, Weinberg, Marc S., Little, Melvyn, Weiss, Stefan F. T.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4080222/
https://ncbi.nlm.nih.gov/pubmed/24990253
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep05556
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